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Lavanya, K.
- A Study on Clinical Profile of Patients with Acute Severe Pancreatitis on Carbapenem Versus Non-Carbapenems
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Authors
Affiliations
1 Koringa College of pharmacy, Korangi, East Godavari Dist., - 533462, Andhra Pradesh, IN
2 Koringa College of Pharmacy, Korangi-533461, Tallarevu (M), East Godavari Dist., Andhra Pradesh, IN
1 Koringa College of pharmacy, Korangi, East Godavari Dist., - 533462, Andhra Pradesh, IN
2 Koringa College of Pharmacy, Korangi-533461, Tallarevu (M), East Godavari Dist., Andhra Pradesh, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 4, No 6 (2012), Pagination: 349-352Abstract
The present study focussed on the clinical profile of patients with acute severe pancreatitis on carbapenem Vs. non carbapenems. Out of 55 patients 22 patients were given carbapenem antibiotics and rest were given non carbapenem antibiotics which comprises of cephalosporins, fluoroquinolones, Piperacillin+tazobactum, Metronidazole. In the carbapenem group 20 patients were initially on cephalosporins and later they were started on carbapenem as they were not improving. In these 20 patients, renal failure is observed in 14 patients and respiratory failure in 6 patients. All these 20patients survived and they stayed in hospital for 3-5 weeks. Two patients in carbapenem group died and they had renal and respiratory failure even they were started on carbapenem in the first week. These two patients stayed in hospital for 3weeks. A total of 33 patients were given non carbapenem antibiotics. Out of 33 patients 16 patients had renal failure and 12 patients had multiorgan failure. 8 patients had local complications in form of multiple fluid collections and necrosis more than 50%. 22 out of patients received cefaperazone+sulbactum with Fluoroquinolones. 7 patients received only Piperacillin+Tazobactum with Fluoroquinolones. 4 patients received only Fluoroquinolones. 30patients who were on cephalosporins stayed 2-3 weeks and all 30 patients improved and were discharged. 3 Patients out of 33 died in the first week due to multiorgan failure. This study conclude that cefaperazone sulbactum along with quinolone is a good first choice antibiotic and reserve the imipenem for sicker and non responders to cephalosporins.Keywords
Acute Severe Pancreatitis, Carbapenem Antibiotics, Non-Carbapenem, Respiratory Failure, Multiorgan Failure, Fluoroquinolones.
References
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- Extraction and Visualization of a Molecular Pathway Using Natural Language Processing System
Abstract Views :181 |
PDF Views:5
Authors
Affiliations
1 Department of Information Technology, Periyar Maniammai University, Thanjavur, IN
1 Department of Information Technology, Periyar Maniammai University, Thanjavur, IN
Source
Artificial Intelligent Systems and Machine Learning, Vol 2, No 6 (2010), Pagination:Abstract
In recent year Natural Language Processing (shortly NLP) is a very attractive method of human-computer interaction. The importance of extracting biomedical information from scientific publications is well recognized. A number of information extraction systems in the biomedical domain. In this paper present extraction, visualization and analysis the present in the biomedical system. We present GENIES, that extracts and structures information about cellular pathways from the biological literature in accordance with a knowledge We implemented GENIES by modifying an existing medical natural language processing system, MedLEE and performed a preliminary evaluation study. Our results demonstrate the value of the underlying techniques for the purpose of acquiring valuable knowledge from biological journals.Keywords
Natural Language Processing, Information Extraction, MedLee.- Design, Development and Evaluation of Buccal Tablets of Pregabalin
Abstract Views :142 |
PDF Views:1
Authors
T. Srikrishna
1,
K. Mohammad Anees
1,
S. Lakshmi Priyanka
1,
K. Lavanya
1,
B. Mounika
1,
M. Murali Krishna
1
Affiliations
1 Department of Pharmaceutics, Narayana Pharmacy College, Chinthareddypalem, Nellore-524002 A.P., IN
1 Department of Pharmaceutics, Narayana Pharmacy College, Chinthareddypalem, Nellore-524002 A.P., IN
Source
Research Journal of Pharmacy and Technology, Vol 10, No 2 (2017), Pagination: 579-588Abstract
The present investigation is concern with formulation and evaluation of mucoadhesive buccal tablets containing anti convulsant drug. Pregabalin to circumvent the first pass effect and to improve its bioavailability with reduction in dosing frequency and dose related side effects. The tablets were prepared by direct compression method. Nine formulations were prepared with different polymers like carbopol, HPMC, Xanthan gum with varying concentration. The tablets were tested for weight variation, hardness, drug content uniformity, swelling index and in vitro drug dissolution study. FTIR studies showed no evidence on interactions between drug and polymer. The in vitro release of Pregabalin was performed under sink conditions (Phosphate buffer PH 7.2, 37 ± 0.5°C) using dissolution apparatus USP type II. The best in vitro drug release profile was achieved with the formulation F6 which contains the drug, HPMC (30 mg). The formulation F6 containing 50 mg of Pregabalin exhibited 8 hrs sustained drug release i.e. 99.01%. The in vitro release kinetics studies reveal that formulation fits with Korsmeyer-Peppas model and mechanism of drug release is anolomus diffusion.Keywords
Bioavailability, Drug Release, Sustained Release, Pregabalin, Buccal Tablets, Carbopol.- A Compact Octagonal Patch Antenna With U-Shaped Slot and DGS For UWB Applications
Abstract Views :101 |
PDF Views:1
Authors
Affiliations
1 Department of Electronics and Communication Engineering, Rajiv Gandhi College of Engineering College, IN
1 Department of Electronics and Communication Engineering, Rajiv Gandhi College of Engineering College, IN
Source
ICTACT Journal on Communication Technology, Vol 13, No 2 (2022), Pagination: 2668-2672Abstract
In this article, an octagonal patch antenna with U-shaped slot for UWB application is proposed. The antenna consists of a three-layered section such as patch, Substrate and Ground. Here, Patch and Ground are the perfectly conducting foil mounted on a Flame Retardant 4 (FR -4) dielectric material whose permittivity Ɛr = 4.4 and loss tangent δ = 0.002. The radiating element and ground are fed through a microstrip line using a Lumped Port. A U- shaped slot is etched on the center of patch to disseminate the surface current throughout the patch whose sectional area is 15 x 15 mm2. Also, a Defective ground Structure is introduced in the ground plane which is provides broadened bandwidth, enriched gain, improvises the radiation characteristics of the antenna with mutual coupling between the proximate sectional areas. The complete measurement of the proposed antenna is 28 x 28 x 1.6 mm3. The antenna is design and analyzed using High Frequency Simulator software (HFSS) platform. The simulated outputs of the antenna such as Reflection Co-efficient, Voltage Standing Wave Ratio (VSWR), Fractional Bandwidth (FBW), Peak Gain, Radiating Efficiency and Impedance Matching are obtained and compare with the existing designs. Thus, the proposed antenna resonates with the bandwidth of 3.7 GHz to 13.5 GHz whose Fractional Bandwidth (FBW) is 114% with a peak gain of 5.6 dBi are obtained, which denotes that the antenna is capable of radiating for UWB applications.Keywords
Antenna Configuration, FR-4, Octagonal Patch, UWB ApplicationsReferences
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- E. Aravindraj and K. Ayyappan, Design of Slotted H-Shaped Patch Antenna with Dumbbell Shaped DGS for 3.5 GHz WiMAX Applications, Indian Journal of Innovations and Developments, Vol. 5, No. 2, pp. 1-6, 2016.
- E. Aravindraj, G. Nagarajan and R. Senthil Kumar, “Design and Analysis of Recursive Square Fractal Antenna for WLAN Applications”, Proceedings of International Conference on Emerging Trends in Information Technology and Engineering, pp. 1-5, 2020.
- E. Aravindraj, G. Nagarajan and R. Senthil Kumar, “A Monopole Octagonal Sierpinski Carpet Antenna with Defective Ground Structure for SWB Applications”, Lecture Notes in Electrical Engineering, Vol. 749, pp. 267-280, 2021.
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- Abhik Gorai,Manimala Pal and Rowdra Ghatak, “A Compact Fractal Shaped Antenna for Ultra-wideband and Bluetooth Wireless Systems with WLAN Rejection Functionality”, IEEE Antennas and Wireless Propagation Letters, Vol. 10, pp. 2163-2166, 2020.
- Debolina Sur and Anand Sharma, “A Novel Wideband Minkowski Fractal Antenna with Assistance of Triangular Dielectric Resonator Elements”, International Journal of RF and Microwave Computer - Aided Engineering, Vol. 29, No.2, pp. 1-11. 2020.
- Lakshmi Charan Tangisetti, T.V. Rama Krishna and K. Kumar Naik, “A Compact UWB Microstrip Antenna with Hexagonal Circular Patch and Asymmetric CPW-Fed for On-body Applications”, International Journal of Emerging Trends in Engineering Research, Vol. 8, No. 2, pp. 1-13, 2020.
- Dhanashree Yadav, Mahesh Mathpati, Mohammed Bakhar, DipaliAtkale and Shabdali Deshpande, “A Wideband Pentagonal Patch Antenna with Rectangular Slots for Wireless Applications”, Proceedings of International Conference on Communication and Information Processing, pp. 1-12, 2022.
- Arashpreet K. Sohi and Amanpreet Kaur, “A Complementary Sierpinski Gasket Fractal Antenna Array Integrated with a Complementary Archimedean DGS for Portable 4G/5G UWB MIMO Communication Devices”, Microwave and Optical Technology Letters, Vol. 62, No. 7, pp. 1-11, 2020.
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